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Dr. Joe Z Tsien is a professor of mloecular biology at Harvard.A.YB.NC.NG

Dr. Joe Z Tsien is a professor of mloecular biology at Harvard.

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更多“Dr. Joe Z Tsien is a professor of mloecular biology at Harvard.A.YB.NC.NG”相关的问题

第1题

Can Drugs Make Us Happier? Samrter?It depends on what is meant by "happy" and "smart."Ther

Can Drugs Make Us Happier? Samrter?

It depends on what is meant by "happy" and "smart."

There are already drugs that brighten moods, like Prozac, and other antidepressants that control levels of a brain chemical called serotonin. While originally meant to treat depression, these drugs have been used for other psychological conditions like shyness and anxiety and even by otherwise healthy people to feel better about themselves.

But is putting people in a better mood really making them happy? People can also drown their sorrows in alcohol or get a euphoric feeling using narcotics, but few people who do so would be called truly happy.

The President's Council on Bioethics said in a recent report that while antidepressants might make some people happier, they can also substitute for what can truly bring happiness: a sense of satisfaction with one's identity, accomplishments and relationships.

"In tike pursuit of happiness human beings have always worried about falling for the appearance of happiness and missing its reality," the council wrote. It added, "Yet a fraudulent happiness is just what the pharmacological management of our mental lives threatens to confer upon us."

Now the race is on to develop pills to make people smarter, at least in one sense. These drugs, several of them already in clinical trials, aim at memory loss that occurs in people with Alzheimer's disease or a precursor called mild cognitive impairment.

But it is lost on no one that if a memory drug works and is safe, it may one day be used by healthy people to learn faster and remember longer.

Studies have already shown that animals can be made to do both whelk the activity of certain genes is increased or decreased. Dr. Tom 'Fully, a professor at Cold Spring Harbor Laboratory, created genetically engineered fruit flies that he said had "photographic memory." In one session, he said, they could learn something that took normal flies 10 sessions.

"It immediately convinced everyone that memory was going to be just another biological process," Dr. Tully said. "There's nothing special about it. That meant that it was going to be treatable and manip-ulable."

But experts say that improving memory will not necessarily make one smarter, in the sense of I.Q. , let alone in wisdom. "It would be a mistake to think that drugs that have an impact on memory necessarily will have an effect on intelligence," said Dr. Daniel L. Schachter, chairman of psychology at Harvard.

Dr. Tully, who is also acting chief scientific officer of Helicon Therapeutics, which is developing memory pills, agreed. "You don't think better than you did before,' he said. "You just get the facts in with less practice. ' Still, he said, that would be significant help to students at exam time.

Any pill used widely by healthy people to improve memory would have to be extremely safe, so that the risks would not outweigh the benefit. Psychological side effects also remain a possibility.

"Is it a good thing to remember everything?" Dr. Tully asked. Could a brain too crammed with information suffer some sort of overload?

Dr. Joe Z. Tsien, a professor of molecular biology at Princeton who genetically engineered smarter mice a few years ago, says he is skeptical that the results can be transferred to people.

"If you look at how people improve their brain power, it's through education," he said. "That has proven to have 100 percent efficiency with minimal side effects."

There are already antidepressants that control levels of a brain chemical called serotonin.

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第2题

Many people dream of having a smarter brain. Princeton neurobiologist Joseph Z. Tsien fo
und the key. In September he announced that he built a better mouse by altering a gene that 【M1】______ affects learning and memory. A similar process of gene manipulation might conceivably be used one day to boost up 【M2】______ intelligence in humans. The secret lies in a feature of brain cells which called the 【M3】______ nomda receptor, which Tsien likes to a cylindrical tube or window 【M4】______ that mediates the flow of information. When the window is open, chemicals called neurotransmitters flow through easily and memory is registered or stored. Tsien noticed that the receptor 【M5】______ worked more efficiently when teamed with the gene NR2B, so he introduced extra NR2B genes into a batch of fertilized mouse eggs. In a normal mouse, the memory window is open in just 【M6】______ 150-thousandths of a second. In Tsiens specifically engineered 【M7】______ mice, the window opens for 250-thousandths of a second, long enough to make a remarkable impression in memory retention. 【M8】______ When he pitted his mice with common mice, they won paws down. 【M9】______ Ordinary mice could recognize a Lego block for 12 hours, but smart mice could remember the block for up to three days. "Thats a profound enhancement," Tsien says. Can it be done with humans? Maybe, so genetic engineering 【M10】______ will have to make some extraordinary advances first. And some thorny ethical issues will have to be resolved. Meanwhile, Tsien promises to keep his furry little geniuses locked up in a lab, far from your larder. "Otherwise," he says, "you might need a smart cat or a smart mousetrap to catch them."

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第3题

听力原文:Researchers have discovered a link between drinking and thinking. A moderate amou

听力原文: Researchers have discovered a link between drinking and thinking. A moderate amount of alcohol may help us keep our mental abilities as we age. Brain scans show alcohol abuse kills brain cells. But little is known about the effects of life long drinking. So moderate drinkers may want to toast new findings from researchers at Duke, and Indiana University. Dr. Joe Christian of Indiana University says men who have one or two drinks each day retain slightly stronger comprehension skills than the non-drinker or the heavy drinker. The doctor and his colleagues give metal tests to nearly 4,000 twins between ages of 66 and 76. The moderate drinkers had slightly better reasoning ability than their brothers or sisters who drink more or less. Other studies have found that alcohol in moderation can help the heart. But alcohol abuse can cause bone loss and other health problems. This study was presented at an alcoholism meeting in San Antonio.

(30)

A.Alcohol helps develop people's intelligence.

B.Heavy drinking is not necessarily harmful to one's health.

C.Controlled drinking helps people keep their wits as they age.

D.Drinking, even moderately, may harm one's health.

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第4题

A "Sloppy Joe" combines cheese and hamburger meat together.A.YB.NC.NG

A "Sloppy Joe" combines cheese and hamburger meat together.

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第5题

I invited Joe and Linda to dinner, but ______ of them came.A.bothB.eitherC.neitherD.none

I invited Joe and Linda to dinner, but ______ of them came.

A.both

B.either

C.neither

D.none

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第6题

Joe slipped because the boat was jumping up and down.A.Right.B.Wrong.C.Doesn't say.

Joe slipped because the boat was jumping up and down.

A.Right.

B.Wrong.

C.Doesn't say.

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第7题

Joe is not good at sports, but when it____________(一提到文学),he is the best in the class

Joe is not good at sports, but when it____________(一提到文学),he is the best in the class.

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第8题

A. At a local club. B. At Joe's house. C. At the sports centre.

A. At a local club.

B. At Joe's house.

C. At the sports centre.

D. At the boarding school.

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第9题

Joe came to the window as the crowd chanted "Joe, Joe, Joe.A.jumped B.maint

Joe came to the window as the crowd chanted "Joe, Joe, Joe.

A.jumped

B.maintained

C.repeated

D.approached

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第10题

Joe came to the window as the crowd chanted“Joe,Joe,Joe.”A. repeatedB. jumpedC. maintaine

Joe came to the window as the crowd chanted“Joe,Joe,Joe.”

A. repeated

B. jumped

C. maintained

D. approached

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