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Alzheimer’s Disease: Are We Close to Finding a Cure?First described in 1906 by Dr.Alois

Alzheimer’s Disease: Are We Close to Finding a Cure?First described in 1906 by Dr.Alois

Alzheimer’s Disease: Are We Close to Finding a Cure?

First described in 1906 by Dr.Alois Alzheimer, Alzheimer s disease is the most common form. of dementia, accounting for around 60%–80% of cases.It is characterized by problems with memory, thinking and behavior.Onset is most common in individuals aged 65 and over, although people in their 40s and 50s can develop what is classed as early - onset Alzheimer’s.

Alzheimer’s is a progressive disease, meaning memory loss is mild in the beginning, but it worsens over time to the extent that individuals are unable to have conversations or respond to their surroundings.There are treatments that have been approved by the US

Food and Drug Administration (FDA) for Alzheimer’s.For example, cholinesterase inhibitors and memantine can help treat memory and thinking problems.But these drugs just help manage the symptoms; there is currently no cure for the disease.

Current Alzheimer’s prevalence in the US makes it the 6th leading cause of death, killing more than half a million seniors every year.To put this in perspective, Alzheimer’s disease currently kills more people each year than prostate cancer and breast cancer combined.There is no doubt that scientists across the world are working hard to find ways to prevent, treat and cure this debilitating condition.Hardly a day goes by without coming across a report about how scientists restored memory and learning deficits in Alzheimer’s mouse models, how vitamin D deficiency could increase the risk of developing dementia, and how DNA methylation in the brain is linked to Alzheimer’s.But what have these studies taught researchers about Alzheimer’s so far?

Preventing and Targeting Plaques and Tangles

As with all diseases, knowing exactly what causes Alzheimer’s is key to identifying ways to prevent and treat the condition.Past research has indicated that Alzheimer’s occurs when two abnormal brain structures — plaques and tangles —damage and kill nerve cells, causing the memory, thinking and behavioral problems associated wit

1.Dementia is not a single disease in itself, but a general term to describe symptoms of impairment in memory, communication, and thinking.()

2.The FDA - approved drugs, like cholinesterase inhibitors and memantine, can cure Alzheimer’s disease.()

3.chronic sleep deprivation may cause these abnormal brain structures.()

4.Tangles are fragments of a protein called beta - amyloid, which build up in areas between nerve cells.()

5.As a result of Alzheimer’s research, there are an array of drugs in development that scientists believe have great potential to effectively treat the disease.()

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更多“Alzheimer’s Disease: Are We Close to Finding a Cure?First described in 1906 by Dr.Alois ”相关的问题

第1题

The passage is mainly about______.A.the development stages of Alzheimer"s diseaseB.the pre

The passage is mainly about______.

A.the development stages of Alzheimer"s disease

B.the pregnancy zone protein

C.a new discovery concerning Alzheimer"s disease

D.patients of Alzheimer"s disease

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第2题

Alzheimer's disease, AD
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第3题

The passage indicates that Alzheimer's is a disease ______.A. common to people, old and yo

The passage indicates that Alzheimer's is a disease ______.

A. common to people, old and young

B. not costly to be cured

C. easy to be handled

D. not easy to be diagnosed

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第4题

Which of the following statements about the Alzheimer's disease is NOT true?A.It was so na

Which of the following statements about the Alzheimer's disease is NOT true?

A.It was so named because Alois Alzheimer first described it.

B.It is the greatest cause of mental deterioration in older people.

C.It can gradually destroy memory and eventually cause death.

D.There are many ways to deal with and cure the disease now.

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第5题

The passage implies that______.A.even doctors can not decide when and where Alzheimer"s di

The passage implies that______.

A.even doctors can not decide when and where Alzheimer"s disease appear

B.it is difficult for some doctors to recognize Alzheimer"s disease sometimes

C.certain memory problems will certainly cause Alzheimer"s disease

D.forgetfulness and memory are something relevant to Alzheimer"s disease

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第6题

The passage indicates that Alzheimer's is a disease ______.A.common to people, old and you

The passage indicates that Alzheimer's is a disease ______.

A.common to people, old and young

B.not costly to be cured

C.easy to be handled

D.not easy to be diagnosed

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第7题

More About Alzheimer's Disease Scientists have developed skin tests that may be used in th

More About Alzheimer's Disease

Scientists have developed skin tests that may be used in the future to identify people with Alzheimer's disease and may ultimately allow physicians to predict who is at risk of getting this neurological disorder.

The only current means of diagnosing the disease in a living patient is a long and expensive series of tests that eliminate every other cause of dementia.

"Since Alois Alzheimer described the disease nearly a century ago, people have been trying to find a way to accurately diagnose it in its early stages," said Patricia Grady, acting director of the National Institute of Neurological Disorders and Stroke in Bethesda, Maryland. "This discovery, if confirmed, could prove a big step forward in our efforts to deal with and understand the disease."

Alzheimer's is the single greatest cause of mental deterioration in older people, affecting between 2.5 million and 4 million people in the United States alone. The devastating disorder gradually destroys memory and the ability to function, and eventually causes death. There is currently no known treatment for the disease.

Researches discovered that the skin cells of Alzheimer's patients have defects that interfere with their ability to regulate the flow of potassium in and out of the cells. The fact that the cell defects are present in the skin suggests that Alzheimer's results from physiological changes throughout the body, and that dementia may be the first noticeable effect of these changes as the defects affect the cells in the brain, scientists said.

The flow of potassium is especially critical in cells responsible for memory formation. The scientists also found two other defects that affect the cells' supply of calcium, another critical element.

One test developed by researchers calls for growing skin cells in a laboratory culture and then testing them with an electrical detector to determine if the microscopic tunnels that govern the flow of potassium are open. Open potassium channels create a unique electrical signature.

A spokesman for the Alzheimer's association said that if the validity of the diagnostic test can be proven it would be important development, but cautioned that other promising tests for Alzheimer's have been disappointing.

The newly developed skin tests may be used in the future to allow doctors to ______.

A.cure those with Alzheimer's disease

B.discover the cause of Alzheimer's disease

C.predict who might get Alzheimer's disease

D.find the consequences of Alzheimer's disease

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第8题

第三篇More About Alzheimer's Disease Scientists have developed skin tests that may be used

第三篇

More About Alzheimer's Disease

Scientists have developed skin tests that may be used in the future to identify people with Alzheimer's disease and may ultimately allow physicians to predict who is at risk of getting this neurological disorder.

The only current means of diagnosing the disease in a living patient is a long and expensive series of tests that eliminate every other cause of dementia.

"Since Alois Alzheimer described the disease nearly a century ago, people have been trying to find a way to accurately diagnose it in its early stages," said Patricia Grady, acting director of the National Institute of Neurological Disorders and Stroke in Bethesda, Maryland. "This discovery, if confirmed, could prove a big step forward in our efforts to deal with and understand the disease."

Alzheimer's is the single greatest cause of mental deterioration in older people, affecting between 2.5 million and 4 million people in the United States alone. The devastating disorder gradually destroys memory and the ability to function, and eventually causes death. There is currently no known treatment for the disease.

Researches discovered that the skin cells of Alzheimer's patients have defects that interfere with their ability to regulate the flow of potassium in and out of the cells. The fact that the cell defects are present in the skin suggests that Alzheimer's results from physiological changes throughout the body, and that dementia may be the first noticeable effect of these changes as the defects affect the cells in the brain, scientists said.

The flow of potassium is especially critical in cells responsible for memory formation. The scientists also found two other defects that affect the cells' supply of calcium, another critical element.

One test developed by researchers calls for growing skin cells in a laboratory culture and then testing them with an electrical detector to determine if the microscopic tunnels that govern the flow of potassium are open. Open potassium channels create a unique electrical signature.

A spokesman for the Alzheimer's association said that if the validity of the diagnostic test can be proven it would be important development, but cautioned that other promising tests for Alzheimer's have been disappointing.

The newly developed skin tests may be used in the future to allow doctors to ______.

A. cure those with Alzheimer's disease

B. discover the cause of Alzheimer's disease

C. predict who might get Alzheimer's disease

D. find the consequences of Alzheimer's disease

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第9题

Who has a lower risk of developing Alzheimer's disease?A.People who have received little e

Who has a lower risk of developing Alzheimer's disease?

A.People who have received little education.

B.People who have mentally active jobs.

C.People who first have good memories.

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第10题

A large epidemiological study also found that using various 100K fruit and vegetabl
e juices contributed to a reduced risk for______.

A Alzheimer’s disease

B inherited disease

C infectious disease

D blood-transmitted disease

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第11题

Which of the following statements about the Alzheimer's disease is NOT true?A. It was so n

Which of the following statements about the Alzheimer's disease is NOT true?

A. It was so named because Alois Alzheimer first described it.

B. It is the greatest cause of mental deterioration in older people.

C. It can gradually destroy memory and eventually cause death.

D. There are many ways to deal with and cure the disease now.

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