More About Alzheimer's Disease Scientists have developed skin tests that may be used in th - 试题答案网问答

第1题

Alzheimer’s Disease: Are We Close to Finding a Cure？First described in 1906 by Dr.Alois

Alzheimer’s Disease: Are We Close to Finding a Cure？

First described in 1906 by Dr.Alois Alzheimer, Alzheimer s disease is the most common form. of dementia, accounting for around 60%–80% of cases.It is characterized by problems with memory, thinking and behavior.Onset is most common in individuals aged 65 and over, although people in their 40s and 50s can develop what is classed as early - onset Alzheimer’s.

Alzheimer’s is a progressive disease, meaning memory loss is mild in the beginning, but it worsens over time to the extent that individuals are unable to have conversations or respond to their surroundings.There are treatments that have been approved by the US

Food and Drug Administration (FDA) for Alzheimer’s.For example, cholinesterase inhibitors and memantine can help treat memory and thinking problems.But these drugs just help manage the symptoms; there is currently no cure for the disease.

Current Alzheimer’s prevalence in the US makes it the 6th leading cause of death, killing more than half a million seniors every year.To put this in perspective, Alzheimer’s disease currently kills more people each year than prostate cancer and breast cancer combined.There is no doubt that scientists across the world are working hard to find ways to prevent, treat and cure this debilitating condition.Hardly a day goes by without coming across a report about how scientists restored memory and learning deficits in Alzheimer’s mouse models, how vitamin D deficiency could increase the risk of developing dementia, and how DNA methylation in the brain is linked to Alzheimer’s.But what have these studies taught researchers about Alzheimer’s so far？

Preventing and Targeting Plaques and Tangles

As with all diseases, knowing exactly what causes Alzheimer’s is key to identifying ways to prevent and treat the condition.Past research has indicated that Alzheimer’s occurs when two abnormal brain structures — plaques and tangles —damage and kill nerve cells, causing the memory, thinking and behavioral problems associated wit

1.Dementia is not a single disease in itself, but a general term to describe symptoms of impairment in memory, communication, and thinking.()

2.The FDA - approved drugs, like cholinesterase inhibitors and memantine, can cure Alzheimer’s disease.()

3.chronic sleep deprivation may cause these abnormal brain structures.()

4.Tangles are fragments of a protein called beta - amyloid, which build up in areas between nerve cells.()

5.As a result of Alzheimer’s research, there are an array of drugs in development that scientists believe have great potential to effectively treat the disease.()

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第2题

More about Alzheimer’s Disease Scientists have developed skin tests that may be used i

More about Alzheimer’s Disease

Scientists have developed skin tests that may be used in the future to identify people with Alzheimer’s disease and may ultimately allow physicians to predict who is at risk of getting this neurological disorder.

The only current means of diagnosing the disease in a living patient is a 1ong and expensive series of tests that eliminate every other cause of dementia.

“Since A1ois Alzheimer described the disease nearly a century ago，people have been trying to find a way to accurately diagnose it in its early stages，”said Patricia Grady，acting director of the National Institute of Neurological Disorders and Stroke in Bethesda，Maryland.“This discovery，if confirmed，could prove a big step forward in our efforts to deal with and understand the disease.”

A1zheimer，s is the single greatest cause of mental deterioration in older people，affecting between 2.5 million and 4 million people in the United States alone．The devastating disorder gradually destroys memory and the ability t0 function，and eventually causes death．There is currently no known treatment for the disease．

Researches discovered that the kin cells of Alzheimer’s patients have defects that interfere with their ability to regulate the now of potassium in and out of the cells．The fact that the cell defects are present in the skin suggests that Alzheimer’s results from physiological changes throughout the body，and that dementia may be the first noticeable effect of these changes as the deflects affect the cells in the brain．scientists said．

The flow of potassium is especially critical in cells responsible for memory formation． The scientists also found two other defects that affect the cells’ supply of calcium，another critical element．

0ne test developed by researchers calls for growing skin cells in a laboratory calture and then testing them with an electrical detector to determine if the microscopic tunnels that govern the now 0f potassium are open． 0pen potassium channels create a unique electrical signature．

A spokesman for the Alzheimer’s association said that if the validity of the diagnostic test can be proven it would he important rlevelopment，but tautioned that 0ther promising tests for Alzheimer’s have been disappointing．

第 46 题 The newly developed skin tests may be used in the future to allow doctors to

A．cure those with Alzheimer’s disease

B．discover the cause 0f Alzheimer’s disease

C．predict wh0 might get Alzheimer’s disease

D．find the consequences of A1zheimer’s disease

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第3题

根据以下材料，回答题More about Alzheimer"s DiseaseScientists have developed skin tests that

根据以下材料，回答题

More about Alzheimer"s Disease

Scientists have developed skin tests that may be used in the future to identify people with Alzheimer"s diseasel and may ultimately allow physicians to predict 51_______ is at risk of getting this neurological disorder.

The only current means of 52_______ the disease in a living patient is a long and expensive series of tests that eliminate every other cause of dementia.

"Since Alois Alzheimer described the 53_______ nearly a century .ago， people have been trying to find a way to 54_______ diagnose it in its early stages， " said Patricia Grady， acting director of the National Institute of Neurological Disorders and Stroke in Bethesda， Maryland. "This discovery， if 55_______ ， could prove a big step forward in our efforts to deal with and understand the disease. "

Alzheimer"s is the single greatest 56_______ of mental deterioration in older people， affecting between 2.5 million and 4 million people in the United States 57_______. The devastating disorder gradually destroys memory and the ability to function， and eventually causes death. There is currently no known 58_______ for the disease.

Researches 59_______ that the skin cells of Alzheimer"s patients have defects that interfere with their ability to regulate the flow of potassium in and out of the cells. The fact that the cell defects are present in the skin suggests that Alzheimer"s 60_______ from physiological changes throughout the body， and that dementia may be the first noticeable 61_______ of these changes as the defects affect the cells in the brain， scientists said.

The flow of potassium is especially critical in cells responsible for memory formation. The scientists also found two other defects that affect the cells" supply of calcium， another 62_______ element.

One test developed by researches calls 63_______ growing skin cells in a laboratory culture and then testing them with an electrical detector to determine if the microscopic tunnels that 64_______ the flow of potassium are open. Open potassium channels create a unique electrical signature.

A spokesman for the Alzheimer"s Association said that if the validity of the diagnostic test can be proven it would be an important 65_______， but cautioned that other promising tests for Aizheimer"s have been disappointing.

回答（51）题查看材料

A.what

B.one

C.it

D.who

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第4题

第三篇More About Alzheimer's Disease Scientists have developed skin tests that may be used

第三篇

More About Alzheimer's Disease

Scientists have developed skin tests that may be used in the future to identify people with Alzheimer's disease and may ultimately allow physicians to predict who is at risk of getting this neurological disorder.

The only current means of diagnosing the disease in a living patient is a long and expensive series of tests that eliminate every other cause of dementia.

"Since Alois Alzheimer described the disease nearly a century ago, people have been trying to find a way to accurately diagnose it in its early stages," said Patricia Grady, acting director of the National Institute of Neurological Disorders and Stroke in Bethesda, Maryland. "This discovery, if confirmed, could prove a big step forward in our efforts to deal with and understand the disease."

Alzheimer's is the single greatest cause of mental deterioration in older people, affecting between 2.5 million and 4 million people in the United States alone. The devastating disorder gradually destroys memory and the ability to function, and eventually causes death. There is currently no known treatment for the disease.

Researches discovered that the skin cells of Alzheimer's patients have defects that interfere with their ability to regulate the flow of potassium in and out of the cells. The fact that the cell defects are present in the skin suggests that Alzheimer's results from physiological changes throughout the body, and that dementia may be the first noticeable effect of these changes as the defects affect the cells in the brain, scientists said.

The flow of potassium is especially critical in cells responsible for memory formation. The scientists also found two other defects that affect the cells' supply of calcium, another critical element.

One test developed by researchers calls for growing skin cells in a laboratory culture and then testing them with an electrical detector to determine if the microscopic tunnels that govern the flow of potassium are open. Open potassium channels create a unique electrical signature.

A spokesman for the Alzheimer's association said that if the validity of the diagnostic test can be proven it would be important development, but cautioned that other promising tests for Alzheimer's have been disappointing.

The newly developed skin tests may be used in the future to allow doctors to ______.

A. cure those with Alzheimer's disease

B. discover the cause of Alzheimer's disease

C. predict who might get Alzheimer's disease

D. find the consequences of Alzheimer's disease

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第5题

Ever spent half an hour looking for your car keys？ Or walked into a room only to wonder wh

at you walked in there to look for？ Or forgotten what day of the week it is？ Not to worry. Occasional memory lapses are normal and not, as you might secretly fear, an early sign of Alzheimers disease. Still, its sometimes difficult even for doctors to recognize where normal forgetfulness stops and more serious memory problems begin. A guidebook published recently by the American Medical Association should make the job easier. The text, Diagnosis, Management and Treatment of Dementia : A Practical Guide for Primary Care Physicians, is somewhat technical but contains a lot of useful information. You can order the guide for $ 5 by calling 1-312-464-5563. Most cases of dementia, or prolonged mental confusion are usually caused by Alzheimers disease. But you should also look for memory problems caused by taking one or more medications. The combination of Tagamet and Valium, for example, can cause a build-up of the tranquilizer in the body. So be sure to tell your doctor every medication you or a loved one is taking, including over-the-counter medicine and dietary supplements. Dont overlook depression. Social isolation or the death of friends and family can shatter anyones mental state but it is particularly difficult to bear with advancing age. Even patients with clear-cut dementia and depression are less confused when their depression is treated. Dont give up even if you or a loved one is diagnosed with Alzheimers disease. Although there is no cure yet there is still a lot you can do to ensure the best quality of life. Start by having a frank conversation about treatment options, and appoint someone as a health-care proxy to make sure those plans are carried out. Most patients with early Alzheimers can still make good decisions about their future care. There are several clinical trials currently studying various treatments. An intriguing one will determine whether vitamin E or an Alzheimers drug called Aricept can prevent dementia from developing in people who are at greater risk of developing Alzheimers disease because they have what is called mild cognitive impairment. To learn more about these clinical studies visit www. alzheimers. org/trials. If you are caring for someone with dementia, be sure you also take care of yourself. You might want to check out the website of the U. S. Alzheimers Association(www. alz. org)for more information. Whether you suffer dementia or love someone who does, the condition is difficult enough to cope with without trying to face it alone.

What is the authors purpose of writing this passage？

A．To define what Alzheimer"s disease is.

B．To tell people how to avoid Alzheimer"s disease.

C．To provide information related to a book on dementia.

D．To persuade people to buy medicine for dementia.

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第6题

"Motherhood may make women smarter and may help prevent dementia（痴呆) in old age by bathi

"Motherhood may make women smarter and may help prevent dementia(痴呆) in old age by bathing the brain in protective hormones," US researchers reported on Thursday.

Tests on rats show that those who raise two or more litters of pups do considerably better in tests of memory and skills than rats who have no babies, and their brains show changes that suggest they may be protected against diseases such as Alzheimer's dementia (早老痴呆症). University of Richmond psychology professor Craig Kinsley believes his findings will translate into humans.

"Our research shows that the hormones of pregnancy (怀孕) are protecting the brain, including estrogen (雌激素), which we know has many neuroprotective (保护神经的) effects," Kinsley said.

"It's rat data but humans are mammals just like these animals are mammals," he added in a telephone interview. "They go through pregnancy and hormonal changes."

Kinsley said he hoped public health officials and researchers would look to see if having had children protected a woman from Alzheimer's dementia and other forms of age-related brain decline.

"When people think about pregnancy, they think about what happens to the baby and the mother from the neck down," said Kinsley, who presented his findings to the annual meeting of the Society of Neuroscience in Orlando, Florida.

"They do not realize that hormones are washing on the brain. If you look at female animals who have never gone through pregnancy, they act differently to the young. But if she goes through pregnancy, she will sacrifice her life for her infant--that is a great change in her behavior. that shows the genetic alterations(改变) to the brain. "

How do scientists know "Motherhood may make women smarter"？

A．Some researchers have told them.

B．Many women say so.

C．They know it by experimenting on rats.

D．They know it through their own experience.

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第7题

Which of the following statements about the Alzheimer's disease is NOT true？A．It was so na

Which of the following statements about the Alzheimer's disease is NOT true？

A．It was so named because Alois Alzheimer first described it.

B．It is the greatest cause of mental deterioration in older people.

C．It can gradually destroy memory and eventually cause death.

D．There are many ways to deal with and cure the disease now.

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第8题

Which of the following statements about the Alzheimer's disease is NOT true？A. It was so n

Which of the following statements about the Alzheimer's disease is NOT true？

A. It was so named because Alois Alzheimer first described it.

B. It is the greatest cause of mental deterioration in older people.

C. It can gradually destroy memory and eventually cause death.

D. There are many ways to deal with and cure the disease now.

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第9题

What kind of people is more likely to develop, or suffer from, Alzheimer's？A．People who ar

What kind of people is more likely to develop, or suffer from, Alzheimer's？

A．People who are older than 65.

B．People who are physically weak.

C．People who consume saturated fat.

D．People who consume ordinary oil.

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第10题

What are we told about people suffering from Alzheimer's disease？A．They don't understand t

What are we told about people suffering from Alzheimer's disease？

A．They don't understand the mechanisms of memory.

B．They can't remember who they are.

C．They forget how to perform. simple tasks.

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